
Genome Guardian 2
11 Oct 2026 · (31 days ago) · Full Release
COMBINE WEAPONS in the microscopic shooter with macroscopic depth. BUILD YOUR NANOBOT from hundreds of parts. SURVIVE the microbial onslaught once more in this psychedelic dive to the Abyss, full of mutations, minerals, anomalies and powerup polyps. SHMUP mode turns it into a vertical shoot 'em up!
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Developer & Publisher: Alpherior
About
About this game
Dive back into the microscopic world, radiating with bioluminescent life and unspeakable horrors.Research permanent upgrades to survive a variety of microbes & modes in this massively expanded follow-up to Genome Guardian.
Build your own biomechanical death machine from different parts to define how it shoots, behaves & moves!Make stationary turrets, psychic water sprinkler motorbikes, or maybe a dual-wielding fidget spinner Gundam.
Easily recreate your favourite turrets from the first gameâ¦or combine em' all into one frankenstein monstrosity
Save/Load 24 loadouts
Paint & Pattern customization
Pair DNA nucleotides A (rapidfire), C (precision), G (spread), T (explosive) to discover 70 hybrid bioweapons!
Shotgun + Bomb mix explosives with spread for Blast Shotgun!
SMG + Pistol make an accurate, fast-firing Scout Rifle!
Blast Shotgun + Scout Rifle = something a whole lot crazier!
20-minute runs you can save & resume at any time + improved Endless Mode
Complete side objectives during runs for extra cash
Mine mineral deposits for resources
Trigger powerful Gadget active abilities
Test discovered weapons in the Database
100 bassy electronic tunes with in-game Jukebox accessible any time + Streamer Mode
Auto aim/fire toggles
Localization in 10 languages
Full rebinding for keyboard & gamepad
400% better performance/framerate on high & low-end PCs
Accessibility for colourblindness, motion sickness & arachnophobia
100 Steam achievements
Cloud Save
Plays great on Steam Deck!
Trailers
System requirements
Minimum: Requires a 64-bit processor and operating system OS: Windows 10 Memory: 4096 MB RAM Storage: 1000 MB available space
Features & accessibility
PC system requirements
Minimum: Requires a 64-bit processor and operating system OS: Windows 10 Memory: 4096 MB RAM Storage: 1000 MB available space
Where to buy
official storesReviews
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